Sex, hormones, and health: what trans patients need to know
Understanding the biological differences between male and female bodies helps us provide better, safer healthcare for trans people on hormone therapy.13 February 2026
When we prescribe hormone therapy, we're making real changes to how someone's body works. That's why it matters to understand the underlying biology: what makes bodies different, and how those differences affect health risks and benefits.
This article sets out the practical facts about sex, hormones, and genetics in a straightforward way. Whether you're considering hormone therapy, already taking it, or supporting someone who is, these are the questions that come up most often in my clinic.
Read the full piece to explore how biological sex influences health, what we actually know (and don't know) about trans health outcomes, and what this means for safe, informed decision-making.