The possibility of regret is precisely why clinical guidelines emphasise thorough, careful assessments before any gender affirming treatment begins. Research shows that comprehensive evaluations help ensure young people are genuinely transgender before starting any pathway, particularly treatments with lasting effects like hormones.
Evidence indicates that regret rates following gender affirming care are relatively low when proper assessment protocols are followed. However, clinicians must balance the small risk of regret against the documented harms of withholding appropriate care. Studies demonstrate that denying treatment to many transgender young people to prevent regret in a few can cause significant psychological distress, including increased rates of depression and anxiety in those who would benefit from care.
Guidelines recommend that transgender young people receive the same standard of care as other children, which involves careful assessment followed by appropriate treatment when clinically indicated. This approach recognises that whilst the possibility of regret exists, it should not prevent access to evidence-based care for those who need it. Mental health support remains available throughout the process to help young people and families navigate any concerns that may arise.